The Convention of International Trade of Endangered Species of Wild Fauna and Flora (“CITES”) is praised as a successful international treaty in protecting and preserving endangered species. However, the effectiveness of CITES is reliant upon member States enforcing and implementing CITES provisions. Colombia has enacted laws implementing CITES but has experienced an increase in the number of endangered species despite these laws. On the other hand, the United States’ implementation of CITES through the Endangered Species Act (“ESA”) is viewed as a sophisticated and successful CITES implementation programs. This thesis makes an attempt to offer viable proposals to help improve the current endangered species protection system in Colombia. To achieve this goal, the existing U.S. and Colombian legal frameworks are compared and contrasted. Finally, a series of recommendations are offered to the Colombia’s species protection in view of the ESA.